Biokemisk forklaring på Multiple Chemical Sensitivity

Med over 600 referencer er artiklen "Multiple Chemical Sensitivity: It's time to catch up to the science" en meget grundig gennemgang af den mulige biokemi bag Multiple Chemical Sensitivity (MCS). 

Highlights fra artiklen:

• Functional imaging studies demonstrated multiple brain changes in MCS.
• These brain regions express TRPV1 and TRPA1 receptors.
• TRPV1 and TRPA1 receptors are sensitized in MCS.
• Similar brain regions are involved in comorbid physical and psychological conditions.
• TRP receptor hypersensitivity may contribute to comorbidity in MCS.

Reference: Molot J, Sears M, Anisman H. Multiple chemical sensitivity: It's time to catch up to the science. Neurosci Biobehav Rev. 2023 Aug;151:105227. doi: 10.1016/j.neubiorev.2023.105227. Epub 2023 May 10. PMID: 37172924.

https://www.sciencedirect.com/science/article/pii/S0149763423001963

Tidligere blogindlæg om MCS og TRPA1: 

Transient Receptor Potential in Multiple Chemical Sensitivity

http://followmeindenmark.blogspot.com/2013/02/transient-receptor-potential-in.html

Multiple Chemical Sensitivity, TRPA1 og aktivering af det autonome nervesystem og immunforsvaret

http://followmeindenmark.blogspot.com/2014/08/multiple-chemical-sensitivity-trpa1-og.html

A role for TRPs in ME/CFS/POTS/MCS/pain/endothelial dysfunction...?

http://followmeindenmark.blogspot.com/2014/02/a-role-for-trps-in-mecfspotsmcspainendo.html