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mandag den 25. marts 2019

One-Carbon metabolism in ME

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ME patients have dysregulated one-carbon metabolism (1). One-carbon metabolism has thoroughly been described in ref 2. An easy to read d...
fredag den 22. marts 2019

Chitotriosidase in ME

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The enzyme chitotriosidase is involved in immune response to chitin-containing pathogens. Chitin is a polymer of N-acetylglucosamine. Chit...
fredag den 15. marts 2019

What does 1-pyrroline-5-carboxylate do to ME?

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ME patients had increased plasma levels of 1-pyrroline-5-carboxylic acid (P5C) and arginine. Females had increased OH-proline (1). P5C is ...
torsdag den 14. marts 2019

Fatty acid oxidation, CPS1 and urea cycle in ME

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When beta-oxidation of fatty acids is blocked, there is an increase in omega-oxidation, which produces dicarboxylic acids (adipic, suberic a...
mandag den 11. marts 2019

Polyamines, 5'-methylthioadenosine and symmetrical dimethylarginine in ME

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The polyamines (putrescine, spermidine and spermine) are involved in replication, transcription, translation, and stabilization of macro-mol...
tirsdag den 26. februar 2019

ME minder om medfødt metabolisk defekt

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Vores mad indeholder kulhydrater, protein og fedt, som vi ved fordøjelse nedbryder til henholdsvis glukose, aminosyrer og fedtsyrer. Disse b...
fredag den 28. december 2018

Flippase, floppase and scramblase

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The cell membrane is composed of cholesterol and phospholipids arranged in a lipid bilayer (outer and inner monolayer). There is a asymmet...